USK Conferences, The 1st Syiah Kuala International Conference on Medical and Health Sciences

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Understanding Neutrophils: How it Moves
Nur Wahyuniati, Ichsan .

Date: 2017-05-11 06:30 PM – 07:00 PM
Last modified: 2017-06-06

Abstract


Neutrophils are one of the most important cellular defense components of the innate immune system. Neutrophils respond to various infectious and inflammatory signals, then it rapidly leads to the site of the lesion via vascular micro-transit and trans-epithelial migration. During this process, neutrophils are constantly undergoing adhesion, detachment, deformation, recovery, extension and contraction processes. Neutrophils are one of the cells in the human body that most often show amoeboid movement. To carry out its duties in the destruction of foreign microorganisms that invade the body, neutrophils must integrate activities that include chemotaxis and phagocytosis. Mechanism of neutrophil movement still leaves many gaps to be studied. As it functions in non-specific immune systems, neutrophils must be able to adjust their cell movements based on invasive agents that attack the human body.


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